Capability
Small Molecule Drug Product CDMOs
Compare CDMOs specializing in small molecule drug product formulation, tableting, encapsulation, and coating. Filter by dosage form, batch size, and regulatory approvals.
50 companies listed
Small molecule drug product manufacturing turns your API into the tablet, capsule, or injectable a patient actually takes. The hard part isn't making one clinical batch. It's finding a partner who can carry the process from a 20,000-unit Phase I lot to a validated commercial line without a mid-program tech transfer that resets your timeline. Ask three things before you shortlist. Does the CDMO run your dosage form at both clinical and commercial scale under one roof? If your molecule is BCS Class II or IV, do they have real bioavailability-enhancement experience (spray drying, hot melt extrusion, amorphous solid dispersions), or just a brochure? And can they show a batch record and stability package that held up under an FDA pre-approval inspection? The CDMOs below list small molecule drug product as a core capability.
About Small Molecule Drug Product Manufacturing
Small molecule drug product manufacturing transforms the API into the final dosage form patients receive. This includes granulation, blending, compression (tablets), encapsulation, film coating, and packaging. Each step requires precise process control to ensure dose uniformity, dissolution performance, and stability.
Bioavailability enhancement is a growing need. Many new chemical entities have poor aqueous solubility (BCS Class II/IV), requiring advanced formulation technologies: spray drying, hot melt extrusion, nanoparticle milling, amorphous solid dispersions, and lipid-based drug delivery systems. CDMOs with these capabilities command premium positioning.
Companies (50)
Axio BioPharma
United States
Axio BioPharma is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Osmopharm S.A.
Switzerland
Osmopharm S.A. is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Avara Pharmaceutical Services
United States
Avara Pharmaceutical Services is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
7bridges (the7bridges.com)
United Kingdom
7bridges (the7bridges.com) is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Matrix Fine Chemical
Switzerland
Matrix Fine Chemical is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Bend Bioscience
United States
Bend Bioscience is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Kemwell Biopharma Private Limited
India
Kemwell Biopharma Private Limited is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
L
Laboratorio Reig Jofre, S.A.
Spain
Laboratorio Reig Jofre, S.A. is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
L
Luina Bio (now AcuraBio)
Australia
Luina Bio (now AcuraBio) is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Monument Chemical bvba
Belgium
Monument Chemical bvba is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
J
Juzen Chemical Corp
Japan
Juzen Chemical Corp is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Gattefossé S.A.
China
Gattefossé S.A. is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
OPKO HEALTH
Israel
OPKO HEALTH is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Cohance Lifesciences
India
Cohance Lifesciences is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Adelco SA
Greece
Adelco SA is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
BioReliance (Merck KGaA, MilliporeSigma)
Scotland
BioReliance (Merck KGaA, MilliporeSigma) is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Bruker Corporation
Switzerland
Bruker Corporation is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
MIDAS CARE PHARMACEUTICAL PVT. LTD.
India
MIDAS CARE PHARMACEUTICAL PVT. LTD. is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Hitech Health
Ireland
Hitech Health is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Cellab CDMO
Andorra
Cellab CDMO is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
C
China Resources Zizhu Pharmaceutical Co., Ltd.
China
China Resources Zizhu Pharmaceutical Co., Ltd. is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
M
Mithra Biotechnology Inc
Taiwan
Mithra Biotechnology Inc is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Bliss GVS Pharma Ltd.
India
Bliss GVS Pharma Ltd. is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Pell Tech Healthcare Pvt. Ltd.
India
Pell Tech Healthcare Pvt. Ltd. is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Tosoh Europe B.V.
Japan
Tosoh Europe B.V. is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Bioprox SA (Bioprox Cultures / Bioprox Healthcare)
France
Bioprox SA (Bioprox Cultures / Bioprox Healthcare) is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
TRADICHEM / TRADICHEM Industrial Services
Spain
TRADICHEM / TRADICHEM Industrial Services is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Miltenyi Bioindustries (Miltenyi Biotec)
Germany
Miltenyi Bioindustries (Miltenyi Biotec) is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
UPM Pharmaceuticals
United States
UPM Pharmaceuticals is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Macrocyclics, Inc.
United States
Macrocyclics, Inc. is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Kinaxis
Canada
Kinaxis is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
K
Kuehne+Nagel
Switzerland
Kuehne+Nagel is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
STC Biologics
United States
STC Biologics is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
B
B+P Logistics GmbH
Germany
B+P Logistics GmbH is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Lodaat Pharma
United States
Lodaat Pharma is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Pravesha Industries Private Limited
India
Pravesha Industries Private Limited is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
NextPharma
Finland
NextPharma is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
AEQUILIBRIUM PHARMA S.r.l.
Italy
AEQUILIBRIUM PHARMA S.r.l. is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Versiti
United States
Versiti is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
MEGGLE (Business Unit Excipients)
Germany
MEGGLE (Business Unit Excipients) is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
PeptART Bioscience GmbH
Switzerland
PeptART Bioscience GmbH is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Algae Products International Ltd
Qatar
Algae Products International Ltd is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Evergen (formerly RTI Surgical)
United States
Evergen (formerly RTI Surgical) is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Dishman Carbogen Amcis Ltd
China
Dishman Carbogen Amcis Ltd is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
RD‑Biotech
France
RD‑Biotech is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
S
STASON PHARMACEUTICALS, INC.
United States
STASON PHARMACEUTICALS, INC. is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
Chronopost
France
Chronopost is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
P
PacificPharma Corp.
Finland
PacificPharma Corp. is a leading contract development and manufacturing organization headquartered in Finland. We specialize in Cell & Gene Therapy, Fill/Finish, Contract Research Organization (CRO) with state-of-the-art facilities serving clients globally.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
E
ElitePharma LLC
Israel
ElitePharma LLC is a leading contract development and manufacturing organization headquartered in Israel. We specialize in Fill/Finish, Small Molecule API Manufacturer, Formulation Development with state-of-the-art facilities serving clients globally.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
E
EliteTherapeutics B.V.
Italy
EliteTherapeutics B.V. is a leading contract development and manufacturing organization headquartered in Italy. We specialize in Fill/Finish, Clinical Trial Materials, Cell & Gene Therapy with state-of-the-art facilities serving clients globally.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Frequently Asked Questions
What equipment is needed for oral solid dose manufacturing?+
Core equipment includes: high-shear granulators, fluid bed processors, roller compactors (for dry granulation), tablet presses (rotary for high-volume, single-station for development), capsule fillers, film coating systems (pan coaters), blenders, and packaging lines. For modified-release products, add multiparticulate processing equipment (pelletizers, coating systems for beads/pellets).
How do you select a drug product CDMO for clinical vs commercial?+
Clinical-stage needs: flexibility, small batch capability (5,000-50,000 units), fast turnaround, and regulatory filing support. Commercial-stage needs: high-throughput equipment, validated processes, supply chain reliability, and cost efficiency at scale. Some CDMOs cover both stages; others specialize. Plan your CDMO strategy to minimize tech transfers between clinical and commercial.
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