Country
Contract Development & Manufacturing Organizations in the United States
The deepest CDMO market in the world. Compare FDA-registered US contract manufacturers across biologics, sterile fill-finish, oral solid dose, and API — by capability, certification, and manufacturing site.
536 companies listed
Manufacturing sites in United States
The US CDMO landscape
The United States is the largest pharmaceutical manufacturing market on earth, with more FDA-registered drug-manufacturing facilities than any other country. For US-market products, a domestic CDMO collapses the regulatory distance to the FDA, removes import friction, and shortens the cold chain for temperature-sensitive biologics — advantages that compound on commercial-scale programs.
Manufacturing clusters are geographically distinct. The Boston–Cambridge corridor anchors biologics and cell & gene therapy. North Carolina's Research Triangle carries deep small-molecule and drug-product capacity. San Francisco and San Diego anchor West Coast biologics, while the I-95 mid-Atlantic and the Midwest hold large-scale sterile and oral-solid-dose plants.
The BIOSECURE Act has made US capacity a strategic question, not just a logistics one. Sponsors that previously relied on certain offshore CDMOs are actively reshoring biologics and cell-therapy work to domestic partners, tightening capacity and making early engagement with a US CDMO more important than at any point in the last decade.
Companies (60)
AbbVie Contract Manufacturing (AbbVie CMO)
United States
ABITEC Corporation
United States
ABL (ABL, Inc. / ABL Europe)
United States
ABL Inc.
United States
Abzena
United States
A
Ackley Machine Corporation
United States
ACON Pharmaceuticals
United States
Acro Biosystems
United States
Actylis
United States
Adare Pharma Solutions
United States
Adesis Inc
United States
ADM Deerland Probiotics & Enzymes
United States
A
Advanced Analytical Testing Laboratories
United States
Advanced Instruments
United States
A
Advanced Medicine Partners
United States
A
Advanced Therapies
United States
Advancion Corporation
United States
A
Aenova Group
United States
Afton Scientific
United States
AGC (AGC Biologics & AGC Pharma Chemicals)
United States
Agilent
United States
Agno Pharmaceuticals
United States
A
Ajay Europe Sarl (Ajay‑SQM)
United States
Ajinomoto Bio-Pharma Services
United States
Akron Biotech
United States
Albemarle
United States
Alcami
United States
Aldevron
United States
Alfasigma (Morpho CDMO)
United States
Alira Health
United States
A
Aliri Bioanalysis
United States
AllCells
United States
Almac Group
United States
Alsico
United States
Altasciences
United States
Aluflexpack Group
United States
Amarex Clinical Research, LLC
United States
AmbioPharm
United States
American Injectables
United States
AmericanBio, Inc.
United States
Ameripharma Labs
United States
A
AMPAC Analytical (an SK pharmteco company)
United States
AnaSpec, Inc.
United States
Ancillare
United States
Andelyn Biosciences
United States
ANJAC Health & Beauty
United States
Antheia Bio
United States
Aphena Pharma Solutions
United States
ApiJect Systems
United States
Applied Laboratories, Inc.
United States
Applied StemCell
United States
A
AptarGroup Inc
United States
A
Aptuit LLC
United States
Aragen Life Sciences Ltd.
United States
Ardena
United States
Argenta (Animal Health CRO/CDMO)
United States
Argonaut Manufacturing Services
United States
ARL Bio Pharma
United States
Arterex (medical device CM)
United States
Arvato (Healthcare)
United States
Frequently Asked Questions
How many CDMOs are in the United States?+
CDMO Hub lists hundreds of contract manufacturers with at least one US manufacturing site — the largest single-country roster in the directory. The live count and ranked list above reflect verified facilities, not just company headquarters, so it tracks where drugs are actually made.
Are US CDMOs FDA-registered?+
US drug-manufacturing facilities must register with the FDA and are subject to routine cGMP inspection. Many also hold EU GMP certification for export to Europe. Always confirm a specific facility's registration and inspection history before contracting — registration status and the relevant product modality both matter.
How does the BIOSECURE Act affect choosing a US CDMO?+
The BIOSECURE Act restricts US government-funded programs from contracting with companies tied to certain foreign biotech firms of concern. While aimed at government work, it has accelerated a broader reshoring of biologics and cell-therapy manufacturing to US (and European) CDMOs, tightening domestic capacity.
What modalities are US CDMOs strongest in?+
US CDMOs span the full modality range, with particular depth in biologics, cell & gene therapy (Boston cluster), sterile fill-finish, and oral solid dose. For early-phase biologics and advanced therapies, the US offers the densest pool of qualified capacity globally.
Find the right CDMO in United States
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